San Francisco 49ers vs Arizona Cardinals — Week 18 2026

odds, implied totals, defence-vs-position angles, key player props and head-to-head history for San Francisco 49ers at Arizona Cardinals. A free, data-led matchup preview.

San Francisco 49ers

@

Arizona Cardinals

Week 18 · 2026

Kickoff: Mon, 11 Jan, 5:00 am AEDTState Farm Stadium

Defence vs position

ARI defence allows

QB

17.5

#18

RB

24.5

#30

WR

24.6

#15

TE

13.8

#31

SF defence allows

QB

17.5

#18

RB

20.7

#22

WR

26.5

#20

TE

11.9

#24

Showing 2025 DVP — 2026 data populates after Week 4.

Recent meetings

• 2025 Week 11SF 41 @ ARI 22
• 2025 Week 3ARI 15 @ SF 16
• 2024 Week 18SF 24 @ ARI 47
• 2024 Week 5ARI 24 @ SF 23
• 2023 Week 15SF 45 @ ARI 29
• 2023 Week 4ARI 16 @ SF 35
• 2022 Week 18ARI 13 @ SF 38
• 2022 Week 11SF 38 @ ARI 10

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Deeper tools: Matchup Centre (premium projections + full DVP), the Vegas-implied board, and the full NFL schedule.

Team hubs: San Francisco 49ers · Arizona Cardinals · all Week 18 games.